文章摘要
马海勇.替米沙坦氢氯噻嗪双层片处方工艺研究[J].药学与临床研究,2022,30(4):309~310
替米沙坦氢氯噻嗪双层片处方工艺研究
Formulation and Preparation of Telmisartan and Hydrochlorothiazide Bilayer Tablets
投稿时间:2022-02-23  修订日期:2022-08-23
DOI:
中文关键词: 替米沙坦  氢氯噻嗪  双层片  处方工艺
英文关键词: Telmisartan  Hydrochlorothiazide  Bilayer tablets  Formulation process
基金项目:
作者单位E-mail
马海勇 江苏万高药业股份有限公司 himalayarange01@126.com 
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中文摘要:
      目的:研究替米沙坦氢氯噻嗪双层片的处方工艺。方法:采用单因素筛选方法获得双层片的处方组成和制备工艺。结果:本品的溶出曲线和各项质量指标均符合要求,处方工艺合理,质量可控。结论:替米沙坦氢氯噻嗪双层片的处方工艺可靠,质量稳定,适合于工业化生产。
英文摘要:
      Objective: To study the formulation and process of telmisartan and hydrochlorothiazide bilayer tablets. Methods: A single factor method was used to select the formulation composition and preparation technology of the bilayer tablets. Results: The dissolution curve and various quality indexes of the product met the requirements, the formulation process was reasonable, and the quality was controllable. Conclusion: The optimized telmisartan and hydrochlorothiazide bilayer tablets have reliable formulation and stable quality, and are suitable for industrial production.
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